Xiaotian Sun, Zhaoshen Li and Min Li Pages 78 - 82 ( 5 )
Signal transduction has been acknowledged to be involved in various cell biological processes. And it is proved that multiple signaling pathways have been associated with the development and progression of pancreatic cancer, which remains one of the most devastating human diseases. Newly developed drugs targeting these aberrant signaling pathways show bright prospect in improving the therapeutic efficacy and outcome for patients with pancreatic cancer. Here we overview the pancreatic cancer related signaling pathway disorders and the corresponding promising targeted therapeutic regimens.
Pancreatic cancer, signal transduction pathway, therapy.
Department of Medicine, Department of Surgery, The University of Oklahoma Health Sciences Center, 975 NE 10th Street, BRC 1262A, Oklahoma City, OK 73104, USA.